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Updated: Jan 30, 2026

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Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
Published on: November 23, 2012
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在乳房切割过程中使用骨后,PET/CT中增加了FDG的吸收
Michael Jüptner1, Bernd Panholzer2, Anette Friedrichs3
1Department of Nuclear Medicine, Molecular Diagnostic Imaging and Therapy, University Hospital Schleswig-Holstein - Campus Kiel, Kiel, Germany.
The Thoracic and cardiovascular surgeon
|January 28, 2026
概括
在胸腔切除术中使用的骨可以在正子发射断层扫描/计算机断层扫描 (PET/CT) 扫描上增加胸部氧化葡萄糖 (FDG) 的吸收,可能模仿深胸部伤口感染. 这一发现对于对心脏手术后患者PET/CT成像的准确解释至关重要.
科学领域:
- 核医学就是核医学.
- 放射性药理学 是一种放射性药理学.
- 手术瘤学手术瘤学
背景情况:
- 生理愈合和异物反应可以模仿18F-FDG-PET/CT上的感染.
- 骨对骨18F-FDG-PET/CT成像的代谢影响尚不清楚.
- 骨通常用于胸切割期间的血液静止.
研究的目的:
- 评估骨应用对胸部18F-FDG吸收的影响.
- 评估骨在18F-FDG-PET/CT中的代谢表现.
- 为了区分骨文物和深胸部伤口感染.
主要方法:
- 25名先前接受过心脏手术的患者接受了18F-FDG-PET/CT与双重时间点成像.
- 胸部18F-FDG吸收被视觉和定量评估 (SUVmax).
- SUVmax在具有和没有骨的患者之间进行了比较,并且与手术后的时间相关联.
主要成果:
- 带有骨的患者在早期 (4.74±1.28对3.70±1.44) 和晚期图像 (6.62±2.67对4.36±1.44) 中显示出更高的平均胸部SUVmax.
- 骨的使用与正视胸部发现有显著的相关性 (OR=10,p=0.0421).
- 在手术后的时间和胸部SUVmax (ρ=-0.139,p=0.505) 之间没有发现显著的相关性.
结论:
- 在胸腔切除术期间使用骨可能会导致PET/CT上部18F-FDG吸收增加.
- 这种增加的吸收可以在手术后持续数年.
- 在解释18F-FDG-PET/CT对深胸部伤口感染时,考虑骨文物.
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