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Updated: Jan 30, 2026

Building Up a High-throughput Screening Platform to Assess the Heterogeneity of HER2 Gene Amplification in Breast Cancers
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EZH2通过调节上皮质可塑性来指导HER2+乳腺癌的进展

Linshan Liu1,2, Ellie J Massey1,2, Dongmei Zuo2

  • 1Department of Biochemistry, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.

EMBO reports
|January 28, 2026
PubMed
概括

增强Zeste同源2 (EZH2) 驱动激进的HER2+乳腺癌进展和转移. 抑制EZH2会增加雌激素受体的表达,使瘤对内分泌疗法如tamoxifen敏感.

关键词:
乳腺癌 乳腺癌 乳腺癌在 EZH2 中使用.表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.雌激素受体的受体塑性是一种可塑性.

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