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Updated: Jan 30, 2026

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes
10:05

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes

Published on: August 13, 2012

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与肝素硫酸盐复合的GLYCORNA调节了VEGF-A信号传递

Peiyuan Chai1, Sina Kheiri2,3, Andrew Kuo4

  • 1Stem Cell and Regenerative Biology Program, Division of Hematology/Oncology, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.

Nature
|January 28, 2026
PubMed
概括

细胞表面核糖蛋白 (csRNPs) 通过与VEGF-A结合来对抗硫酸介导的信号传递,影响血管发育. 这一发现揭示了血管生成中的新调节轴.

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Methods to Study Mrp4-containing Macromolecular Complexes in the Regulation of Fibroblast Migration

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Sulfate Separation by Selective Crystallization with a Bis-iminoguanidinium Ligand

Published on: September 8, 2016

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Master transcription regulators are regulatory proteins that are predominantly responsible for regulating the expression of multiple genes. Often these genes work in concert to drive a  complex process. Activation of a master transcription regulator can lead to a cascade of transcriptional activation necessary for that outcome. These regulators can directly bind to the regulatory sequences of the various genes involved, or they can indirectly regulate transcription by binding to regulatory...
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