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Updated: Jan 30, 2026

Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells
14:26

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在单细胞分辨率下解决克隆进化和染色体外DNA的选择

Josephine Deleuran Hendriksen1,2,3, Alessio Locallo1,2,3, Balthasar Clemens Schlotmann1,2

  • 1The Finsen Laboratory, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.

Genome biology
|January 29, 2026
PubMed
概括

外染色体DNA (ecDNA) 驱动癌症生长和耐药性. 我们的新计算方法ecSingle揭示了ecDNA在瘤异质性和单细胞水平的进化中的作用.

关键词:
癌症 癌症 癌症 癌症克隆的演化过程中的克隆进化.染色体外DNA是一种DNA.长读序列的测序方式基因放大放大 基因放大一个单细胞的单细胞.

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