童年不良经历与喘之间的关联:对元分析的协议
Liqiong Wang1, Yungai Cheng2, Yuqi Wang3,4
1Department of Mental Health Center, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Children and Adolescents' Health and Diseases, Hangzhou, People's Republic of China.
Systematic reviews
|January 29, 2026
概括
儿童不良经历 (ACE) 与喘发展有关,尽管有争议. 这一系统性审查和元分析将澄清各种ACE与喘之间的关联,旨在改善儿童福祉.
科学领域:
- 儿科健康 儿科健康
- 环境流行病学环境流行病学
- 公共卫生 公共卫生
背景情况:
- 儿童不良经历 (ACE) 越来越多地被认为是慢性健康状况的重要风险因素.
- 关于ACE和喘发展之间的关联是有争议的,需要严格的调查.
- 在PROSPERO注册:CRD42024544950. 在PROSPERO注册:CRD42024544950.
研究的目的:
- 系统地审查和对现有证据进行元分析,以了解各种ACE与喘之间的关联.
- 提供ACEs-喘联系的全面评估,解决当前的争议.
- 为了为减轻儿童暴露在ACE中的喘风险的策略提供信息.
主要方法:
- 将在主要数据库 (PubMed,Embase,Cochrane,Web of Science) 进行系统的文献搜索,直到2025年4月30日.
- 数据提取将包括研究特征,人口统计和特定的ACEs-喘关联.
- 研究质量将使用纽卡斯尔-太华尺度 (NOS) 进行评估;将采用元分析或描述性合成.
主要成果:
- 本节将介绍包括在内的关于各种ACE与喘之间的关联研究的综合发现.
- 在可行的情况下,将进行定量元分析,以确定关系的强度和方向.
- 结果将被清楚地呈现,解决异质性和潜在的偏见.
结论:
- 这次系统性审查和元分析将阐明不同ACE和喘之间的关系.
- 这些发现旨在支持减少喘发病率和改善ACE儿童生活质量的干预措施.
- 该研究为儿童发育和呼吸系统健康领域提供了有力的证据.
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