[经产期结核病呈现为通过支气管镜检查诊断的支气管内结核病:一个病例报告]
Hujun Wu1, Yanfen Lin2, Xiaofen Tao3
1Department of Endoscopy Center, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Children and Adolescents' Health and Diseases, Hangzhou 310052, China. 6515115@zju.edu.cn.
概括
一个患有持续咳的3个月大的婴儿,最初被误诊为肺炎,被发现患有围产期内结核病. 及时的抗结核治疗导致了显著的临床和成像改善.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 患有持续呼吸道症状的婴儿可能难以诊断.
- 肺炎是各种儿科肺部疾病的常见初始误诊.
- 肺内肺结核在新生儿中提出了独特的诊断和管理挑战.
研究的目的:
- 报告婴儿患有围产期内支气管结核病的情况.
- 突出诊断挑战和成功治疗这种罕见的疾病.
- 强调在患有耐火性肺炎的婴儿中考虑结核病的重要性.
主要方法:
- 一个3个月大的男婴的病例介绍,有4周的咳史.
- 诊断工作包括胸部CT,支气管透视与支气管支气管洗,T-SPOT测试和高通量测序.
- 治疗涉及多种药物抗结核治疗方案,包括异亚,利芬素,皮拉津胺和线索利德.
主要成果:
- 对疑似肺炎的初始抗生素治疗是无效的.
- 支气管镜检查显示左侧主要支气管狭窄,带有颗粒瘤和状缩.
- 通过微生物学和分子方法证实了 * Mycobacterium 结核病 * 感染的诊断.
- 一个月的抗结核治疗导致临床症状和肺部成像显著改善.
结论:
- 在患有持久且不治愈的肺炎的婴儿中,应考虑围产期内结核病.
- 早期和准确的诊断对于有效的管理至关重要.
- 组合抗结核病治疗方案,包括linezolid,可以有效治疗严重的婴儿结核病.
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