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PDK4驱动的代谢重编程增强了结肠直肠癌中介质细胞的入侵,以及腹转移

Lingyu Han1,2, Qinyuan Zhang1,2, Yuchen Wu1,2

  • 1Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China.

Acta biochimica et biophysica Sinica
|January 29, 2026
PubMed
概括

酸盐脱酶激酶4 (PDK4) 驱动着结直肠癌的腹转移,通过促进中细胞的入侵. PDK4增强脂肪酸氧化和β-catenin乙化,这是瘤扩散的关键步骤.

关键词:
通过乙化处理.结肠直肠癌是什么意思脂肪酸氧化过程中的脂肪酸氧化.介质细胞细胞介质细胞.腹内转移的发生.

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