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Updated: Jan 30, 2026

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i-Motif,而不是G-quadruplex,稳定性可以调节胰岛素的表达

Dilek Guneri1,2, Christopher J Morris1, Yiliang Ding3

  • 1School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, United Kingdom.

Nucleic acids research
|January 29, 2026
PubMed
概括

人类胰岛素基因的转录激活需要G-四重复和i-动机结构形成. 促进子活性与i-动机稳定性相关,这表明基因调节中的动态相互作用.

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