在关节关节疾病中使用高性乳糖和多氧化核酸 (PDRN) 的prolotherapy的有效性
Jin-Won Choi1, Young-Kyun Kim1,2, Pil-Young Yun1,3
1Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, 13620 Seongnam-si, Republic of Korea.
Journal of oral & facial pain and headache
|January 29, 2026
概括
普罗洛疗法通过减少疼痛和改善功能,有效治疗关节疾病 (TMDs). 德克斯特和PDRN注射都对TMD患者显示出显著的临床益处.
科学领域:
- 整形外科 整形外科 整形外科
- 再生医学是一种再生医学.
- 疼痛管理 疼痛管理
背景情况:
- 关节疾病 (TMDs) 通常会带来治疗挑战.
- 对于一些TMD患者来说,传统疗法可能不足.
- 这项研究重点是针对耐火性TMD病例的前疗法.
研究的目的:
- 评估使用高血压和多氧核酸 (PDRN) 的prolotherapy的临床疗效.
- 评估prolotherapy对患有关节疾病 (TMDs) 的患者疼痛和功能的影响.
- 为了比较德克斯特与PDRN在TMD治疗中的有效性.
主要方法:
- 对66名被诊断为TMD患者的回顾性图表审查.
- 治疗涉及使用高血压牛排糖或PDRN以准关节 (TMJ) 结构的prolotherapy.
- 疼痛 (VAS) 和最大口腔开口 (MMO) 是主要的结果措施;关节声音和部位位移也被分析.
主要成果:
- 前期治疗,平均为2.3次,显著降低了VAS得分 (p < 0.001) 和改善了MMO (p < 0.001).
- 观察到关节声音,部位移和曲的显著减少.
- 德克斯特和PDRN之间没有发现显著差异,两种药物都产生了显著的改善.
结论:
- 普罗洛疗法是一种临床有效的治疗方法,用于改善TMD患者的疼痛和功能.
- 超性乳糖和PDRN都显示出在关节疾病的前期治疗中显著的疗效.
- 这些发现支持prolotherapy作为一个可行的选择来管理耐火TMDs.
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