在偏头痛和纤维肌痛的关节障碍中疼痛调节概况
Pankaew Yakkaphan1, Tara Renton2
1Faculty of Dentistry, Prince of Songkla University, 90110 Songkhla, Thailand.
Journal of oral & facial pain and headache
|January 29, 2026
概括
患有并发性偏头痛和纤维肌痛的关节障碍 (TMD) 患者显示疼痛调节减少. 伴随性疾病削弱疼痛抑制,影响内源性疼痛调制 (EPM) 在这些复杂的疼痛条件.
科学领域:
- 神经科学是一个神经科学.
- 疼痛研究 疼痛研究
- 临床医学 临床医学
背景情况:
- 部疾病 (TMD) 经常与其他疼痛状况并存.
- 在伴随疾病的TMD中对内源性疼痛调制 (EPM) 的研究尚未得出结论.
- 这项研究调查了在患有伴随性偏头痛和纤维肌痛的TMD患者中EPM.
研究的目的:
- 评估患有关节障碍 (TMD) 的个体内源性疼痛调制 (EPM).
- 调查伴随性偏头痛和纤维肌痛对TMD患者EPM的影响.
- 分析与并发症相关的疼痛调节概况 (PMP).
主要方法:
- 评估条件疼痛调制 (CPM) 和时间总和 (TS).
- 包括健康对照组,只有TMD,只有偏头痛,TMD+偏头痛,以及TMD+偏头痛+纤维肌痛组.
- 根据CPM和TS反应将参与者分类为疼痛调节概况 (PMP I-IV).
主要成果:
- 偏头痛,TMD+偏头痛和TMD+偏头痛+纤维肌痛组与对照组相比,疼痛抑制显著减少.
- 没有并发症的TMD患者表现出完整的疼痛调节.
- 增加的并发症与较弱的条件疼痛调制 (CPM) 相关联.
结论:
- 内源性疼痛调节 (EPM) 在没有并发性疼痛病症的TMD患者中是完整的.
- 伴随性疼痛状况,如偏头痛和纤维肌痛,在TMD患者中可能会危及EPM.
- 与并发症相关的疼痛放大和中央敏感化可能会损害疼痛调节能力.
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