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Updated: Jan 30, 2026

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在拉丁美洲胃肠内镜单位应用新型不良事件分类尺度
Oscar Corsi1, Richard Martinez1, Joaquín Aguirre2
1Department of Gastroenterology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago 8330074, Chile.
World journal of gastrointestinal endoscopy
|January 29, 2026
概括
胃肠内镜不良事件 (AE) 的AGREE分类与已建立的ASGE词典有很强的相关性. AGREE是AE评级的可行的替代方案,尽管它将更多的事件归类为非AE.
科学领域:
- 胃肠病学和内镜检查
- 医疗质量和安全 医学质量和安全
- 临床分类系统临床分类系统
背景情况:
- 在胃肠内镜中对不良事件 (AE) 的准确分类对于患者的安全和质量改善至关重要.
- 美国胃肠内镜学会 (ASGE) 词典是一个标准,而胃肠内镜学会 (AGREE) 的AEs分类是一个较新的系统.
- 将这些系统进行比较对于了解它们在现实世界临床环境中的实用性至关重要.
研究的目的:
- 为了比较AGREE和ASGE对胃肠内镜不良事件的分类系统之间的一致性和相关性.
- 评估两种分类系统的性能,使用来自拉丁美洲学术内镜单位的现实数据.
主要方法:
- 在智利的高等医疗中心对内镜相关的AE (2009-2022) 预期注册的回顾性分析.
- 每个AE的独立评分由两个盲目审查员使用ASGE和AGREE系统进行.
- 与科恩的卡帕评估的观察者间一致性;使用斯皮尔曼的等级测试评估的跨尺度相关性.
主要成果:
- 在176,655个手术中,分析了235个AE (0.13%),主要来自治疗干预.
- 最常见的副作用包括心血管事件 (42.1%),出血 (20.9%),以及穿孔 (17.0%).
- ASGE将57.9%的AE归类为AE (Kappa=0.83),而AGREE将54.0%的AE归类为AE (Kappa=0.74),显示出强烈的相关性 (ρ=0.89,P<0.001).
结论:
- AGREE分类显示出与ASGE词典的强烈相关性,用于分级胃肠内镜AEs.
- 与ASGE相比,AGREE将更多事件归类为非AEs,并且显示观察者之间的一致性略低.
- AGREE是AE分级的可行替代方案,特别是在不同的临床环境中.
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