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Updated: Jan 30, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
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I型干扰素驱动系统性红斑狼中明显的CD8+ HLA-DRB1+ T细胞子集的功能障碍

Huizhong Long, Elio Carmona, Mikhail G Dozmorov

    medRxiv : the preprint server for health sciences
    |January 29, 2026
    PubMed
    概括

    系统性红斑狼 (SLE) 具有扩展的CD8+ HLA-DRB1+ T细胞,这些细胞毒性但功能障碍. I型干扰素 (IFN) 驱动这种状态,导致疲劳和降粒失效,这表明SLE的治疗点.

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