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Updated: Jan 30, 2026

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain
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基于由DNA甲基化驱动的差异性表达基因的肝细胞癌预测模型的设计和验证

Geyang Hu1,2, Liang Zhou1,3, Jie Zhang2

  • 1Bengbu Medical College Graduate Department, Bengbu, Anhui, China.

International journal of genomics
|January 29, 2026
PubMed
概括

这项研究使用DNA甲基化和RNA测序数据开发了肝细胞癌 (HCC) 的预测模型. 该模型确定了三种基因,用于预测患者的生存率和耐药性,帮助个性化HCC管理.

关键词:
通过DNA甲基化.药物耐药性 耐药性 药物耐药性表观遗传学是指表观遗传学.肝细胞癌是肝细胞癌.预后 预后 预后

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相关概念视频

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What is Gene Expression?

Overview
Gene expression is the process in which DNA directs the synthesis of functional products, that is, proteins. Cells can regulate gene expression at various stages. It allows organisms to generate different cell types and enables cells to adapt to internal and external factors.
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A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is made up of nucleotides and proteins consist of amino...
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A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is comprised  of nucleotides and proteins are comprised of amino acids, a mediator is required to convert the information encoded in DNA into proteins. This mediator is the messenger RNA (mRNA). mRNA copies the blueprint from DNA by a process called transcription. In eukaryotes, transcription occurs in the nucleus by complementary base-pairing with the DNA template. The mRNA is then...
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Topologically Associated Domains (TADs)
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