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Updated: Jan 30, 2026
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An In Vitro Approach to Photodynamic Therapy
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用二极管激光激活印ocyanine绿色激活光动力疗法在感染的根管中消灭Enterococcus faecalis:一项体外研究
Ali Falah Rfysh1, Mohammed Rahid Hameed2, Saeed Asgary3
1Department of Conservative Dentistry, College of Dentistry, University of Alkafeel, Najaf, Iraq.
Dental research journal
|January 29, 2026
概括
用绿色氨酸 (ICG) 进行光动力学疗法 (PDT) 完全消除了根管中的Enterococcus faecalis 这种ICG-PDT方法是内牙消毒的高效辅助方法.
科学领域:
- 牙周内科医院 牙周内科医院 牙周内科医院
- 微生物学 微生物学
- 生物医学工程 生物医学工程
背景情况:
- 目前的内牙消毒方法可以通过光动力学疗法 (PDT) 增强.
- 据信PDT可以改善根管内的细菌的消除.
- Enterococcus faecalis是内牙感染中常见的病原体.
研究的目的:
- 用不同的光敏感剂评估PDT的抗微生物有效性.
- 评估PDT在感染的根管中对Enterococcus faecalis的疗效.
- 确定用于内牙消毒的最佳PDT协议.
主要方法:
- 一项采用50个感染E. faecalis.的人类上第一个牙的体外研究.
- 根被单独用激光处理,或使用绿色氨酸 (ICG),甲基蓝 (MB) 或 cetrimide (CT) 的PDT.
- 细菌减少量化为殖民地形成单位 (CFU),并进行统计分析.
主要成果:
- 使用ICG进行PDT,实现了E. faecalis (0 CFU/mL) 的完全根除.
- 使用MB和CT的PDT显著降低了细菌负载 (P <0.05).
- 与PDT治疗相比,单独的激光疗法的疗效较低.
结论:
- 在ICG-PDT与810nm二极管激光相结合时,完全根除了E. faecalis.
- 与单独使用MB,CT和激光相比,ICG-PDT显示出更高的抗菌活性.
- ICG-PDT是一种有前途的辅助疗法,用于内牙消毒协议.
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