通过皮肤的左心室附属体,为心脏动在心脏粉症的心脏动的阻塞
Abdul Hakim Almakadma1, Ramzi Ibrahim2, Hoang Nhat Pham3,4
1Department of Medicine Brookdale University Hospital Brooklyn New York USA.
Journal of arrhythmia
|January 29, 2026
概括
与心肌动 (AF) 的心肌粉症 (CA) 患者的左心房附属体封闭 (LAAO) 显示出类似的缺血事件率,但与非CA患者相比,出血风险增加.
科学领域:
- 心脏病学 心脏病学
- 心血管研究研究心血管研究
- 医疗器械 医疗器械
背景情况:
- 心脏粉症 (CA) 经常与心房动 (AF) 一起发生.
- 在患有CA的AF患者中,左心房尾封闭 (LAAO) 后的结局尚未得到充分确立.
- 了解LAAO在CA中的有效性和安全性对于患者管理至关重要.
研究的目的:
- 为了比较LAAO在患有心脏粉症和没有心脏粉症的患者的结果.
- 评估LAAO在CA的AF患者的特定人群中的安全性和有效性.
- 为临床决策提供有关LAAO在CA患者中的数据.
主要方法:
- 使用TrinetX数据库进行回顾性研究.
- 包括接受LAAO的成年心房动患者.
- 1: 1 倾向性得分匹配,以比较心脏粉样化症和没有心脏粉样化症的患者.
- 卡普兰-梅尔分析和考克斯回归用于结果评估.
主要成果:
- 该研究包括532个匹配的患者对 (具有和没有CA).
- 死亡率和主要不良心血管事件在CA和非CA组之间是相似的.
- 患有心肌粉症的患者中,主要出血事件显著增加 (HR 1.90).
结论:
- 左心房尾阻塞 (LAAO) 在心脏粉症 (CA) 和心房动 (AF) 患者中显示出可比的缺血结局益处.
- 在CA患者中,LAAO与严重出血的风险显著增加有关.
- 这些发现强调了在对CA患者进行LAAO时需要仔细考虑出血风险的必要性.
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