肝硬化与囊括性周周硬化:一个病例报告
Emery Boudreau1, Rosemarie Matte2, Christian Wilke3
1Surgery, Dartmouth Hitchcock Medical Center, Lebanon, USA.
Cureus
|January 29, 2026
概括
本案例研究描述了一种异常呈现的腹膜硬化症,这种罕见的疾病会导致腹部组织硬化. 这位患者没有先前透析或移植史,出现了严重的症状,主要影响肝脏,突出显示需要进一步研究.
科学领域:
- 胃肠病学 胃肠病学
- 病理学 病理学 病理学
- 手术病例报告 手术病例报告
背景情况:
- 封装性周周硬化 (EPS) 是一种罕见的疾病,通常与末期病和周周透析有关.
- 在移植后的患者中,EPS通常表现为小肠阻塞.
- 这个病例涉及一个患有肝硬化,慢性血小板缺血和高血压的患者,但没有腹腔透析或移植病史.
研究的目的:
- 报告一个不寻常的晚期硬化腹膜炎病例.
- 要突出一种罕见的腹硬化症表现,主要影响肝脏表面.
- 强调需要对EPS的病理生理学和临床谱进行进一步的研究.
主要方法:
- 一名72岁的男性出现了慢性右上象限疼痛.
- 计划进行 laparoscopic 胆囊切除术,但手术后的检查结果显示密集的纤维化组织包围了肝脏和其他腹部结构.
- 为了进行基因病理学分析,获得了活检,证实了腹硬化症.
主要成果:
- 组织病理学分析证实了腹膜硬化症.
- 患者表现出广泛的纤维化沉积物,主要包围肝脏,在结肠和腹膜上有额外的发现.
- 这种情况是在一个没有经过腹膜透析或移植病史的病人身上诊断出来的,这是一个非常不寻常的表现.
结论:
- 这种病例在没有典型风险因素的患者身上呈现出先进的硬化周周炎的独特表现.
- 肝脏表面的首要参与对于已知的EPS病例来说是不典型的.
- 需要进一步的研究,以了解这种罕见疾病的多样性病理生理学和临床表现.
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