Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

The Evidence for Evolution02:55

The Evidence for Evolution

48.0K
Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.
48.0K
Inhaled Medications01:23

Inhaled Medications

792
Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
792
Pulmonary Ventilation: Inhalation01:24

Pulmonary Ventilation: Inhalation

8.0K
Pulmonary ventilation is a vital process that ensures the exchange of oxygen and carbon dioxide in the lungs. It refers to the movement of air into and out of the lungs, enabling the body to obtain oxygen and remove waste carbon dioxide. In this article, we will explore the intricacies of pulmonary ventilation, including its underlying principles, mechanisms, and the interplay of pressures within the respiratory system.
Boyle's law becomes particularly pertinent when examining respiratory...
8.0K
Inhalational Anesthetics: Overview01:20

Inhalational Anesthetics: Overview

1.1K
Inhalation anesthetics are drugs that induce general anesthesia upon inhalation. They work by increasing the sensitivity of GABAA receptors or inhibiting NMDA receptors, leading to a decrease in central nervous system activity. The depth of anesthesia can be rapidly adjusted by changing the concentration of the inhaled gas. Some common examples of inhalational anesthetics include volatile liquids like isoflurane, desflurane, sevoflurane and gases like xenon and nitrous oxide. Isoflurane, a...
1.1K
Insulin Secretory Vesicles01:05

Insulin Secretory Vesicles

6.8K
Insulin secretory vesicles release insulin to stimulate blood glucose uptake and regulate carbohydrate metabolism. When the blood glucose levels increase, glucose enters the pancreatic β-islet cells through glucose transporters. Once inside, glucose is metabolized through glycolysis, the citric acid cycle, and the electron transport chain, producing ATP. This increase in ATP concentration closes ATP-sensitive potassium channels, leading to depolarization of the membrane and the opening of...
6.8K
Insulin: The Receptor and Signaling Pathways01:28

Insulin: The Receptor and Signaling Pathways

3.1K
Insulin action is mediated through a receptor tyrosine kinase, akin to the IGF-1 receptor. The number of receptors per cell varies significantly, from 40 on erythrocytes to 300,000 on adipocytes and hepatocytes. The insulin receptor consists of linked α/β subunit dimers, forming a heterotetramer glycoprotein with two extracellular α subunits and two β subunits spanning the membrane. The α subunits inhibit the inherent tyrosine kinase activity of the β subunits, but...
3.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Hormones, hormesis, and holistic obesity care.

JPMA. The Journal of the Pakistan Medical Association·2026
Same author

Semaglutide Injection Once-Weekly for Weight Management in Adults: Results From A Randomized Phase III, Active-Controlled Study.

Diabetes, obesity & metabolism·2026
Same author

Efficacy and Safety of the Dual Glucagon-Like Peptide-1 and Glucagon Receptor Agonist Mazdutide in Predominantly Chinese Adults With Obesity and/or Type 2 Diabetes: A Systematic Review and Meta-Analysis.

Diabetes, obesity & metabolism·2026
Same author

Clinical assessment of sexual function in transwomen.

The journal of sexual medicine·2026
Same author

Achondroplasia management in the era of targeted therapies: a meta-analysis of C-type natriuretic peptide analogs.

Journal of the Endocrine Society·2026
Same author

The CKD-OSTEO Score: A Chronic Kidney Disease-specific Tool for Osteoporosis Risk Stratification.

TouchREVIEWS in endocrinology·2026

相关实验视频

Updated: Jan 30, 2026

Decoding Natural Behavior from Neuroethological Embedding
08:00

Decoding Natural Behavior from Neuroethological Embedding

Published on: October 3, 2025

683

解码了吸入胰岛素:消除神话和呈现临床证据

Jothydev Kesavadev1, Hemant P Thacker2,3, Neeta Deshpande4

  • 1Diabetes and Endocrinology, Jothydev's Diabetes & Research Center, Thiruvananthapuram, IND.

Cureus
|January 29, 2026
PubMed
概括

吸入胰岛素为控制血糖提供了一个无针替代方案,解决了注射焦虑和储存问题等挑战. 本综述阐明了Afrezza® (吸入Technosphere®胰岛素) 在糖尿病治疗中的作用.

关键词:
这就是为什么afrezza®.吸入的胰岛素可以吸入.吸入疗法是一种吸入疗法.肺的 肺的 肺的 肺的神话 神话 神话 神话 神话技术圈是一个技术圈.

更多相关视频

Split-Ubiquitin Based Membrane Yeast Two-Hybrid MYTH System: A Powerful Tool For Identifying Protein-Protein Interactions
14:04

Split-Ubiquitin Based Membrane Yeast Two-Hybrid MYTH System: A Powerful Tool For Identifying Protein-Protein Interactions

Published on: February 1, 2010

32.0K
Improving IV Insulin Administration in a Community Hospital
12:08

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

19.4K

相关实验视频

Last Updated: Jan 30, 2026

Decoding Natural Behavior from Neuroethological Embedding
08:00

Decoding Natural Behavior from Neuroethological Embedding

Published on: October 3, 2025

683
Split-Ubiquitin Based Membrane Yeast Two-Hybrid MYTH System: A Powerful Tool For Identifying Protein-Protein Interactions
14:04

Split-Ubiquitin Based Membrane Yeast Two-Hybrid MYTH System: A Powerful Tool For Identifying Protein-Protein Interactions

Published on: February 1, 2010

32.0K
Improving IV Insulin Administration in a Community Hospital
12:08

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

19.4K

科学领域:

  • 内分泌学 在内分泌学.
  • 药理学 药理学是指药理学的学科.
  • 肺部病理学 肺部病理学

背景情况:

  • 普兰迪亚尔胰岛素治疗面临着现实世界的挑战,包括注射焦虑,低血糖风险,体重增加和坚持问题.
  • 餐后高血糖是印度的一个重大问题,需要患者友好的血糖管理策略.
  • 吸入性胰岛素Afrezza®提供了一种无针,快速起作用的选择,模仿生理性胰岛素配置.

研究的目的:

  • 为了澄清吸入胰岛素的临床作用,特别是Afrezza®.
  • 解决常见的神话,并提供基于证据的关于吸入胰岛素使用的见解.
  • 评估Afrezza®的药理动力学 (PK) 和药理动力学 (PD) 概况,疗效,安全性和实际应用.

主要方法:

  • 关于吸入胰岛素 (Afrezza®) 的现有文献的综述.
  • 对药理动力学和药理动力学数据的分析.
  • 检查临床试验结果的疗效,安全性和肺部方面的考虑.
  • 讨论实践方面,包括患者查,教育和禁忌.

主要成果:

  • 阿弗雷扎®表现出迅速发作和短时间的作用,紧密模仿生理胰岛素释放.
  • 证据支持其在1型和2型糖尿病成年患者的疗效和安全性.
  • 已经评估了肺部安全性,并概述了具体的剂量,储存和患者选择标准.

结论:

  • 阿弗雷扎 (Afrezza) 是一种变革性的,方便和有效的替代传统的食前胰岛素注射.
  • 通过螺旋计和全面教育进行适当的患者查对于最佳的Afrezza®利用至关重要.
  • 吸入胰岛素解决了胰岛素治疗的关键障碍,可能改善粘附性和血糖控制.