相关实验视频
Updated: Jan 30, 2026
08:50
Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
16.8K
在晚期慢性病中提供个性化支持的低蛋白饮食:与疾病进展,透析延迟和死亡率相关
Gisella Vischini1, Sara Caissutti2, Daniele Vetrano2
1Nephrology, Dialysis and Kidney Transplant Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Clinical kidney journal
|January 29, 2026
概括
低蛋白饮食 (LPD) 显著降低了替代疗法 (KRT) 的需要,并改善了晚期慢性病 (CKD) 患者的存活率. 超过60%的患者选择了LPD,证明了可行性和潜在的益处.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 饮食科学 饮食科学
- 公共卫生 公共卫生
背景情况:
- 慢性病 (CKD) 管理在预防功能衰竭方面面临挑战.
- 低蛋白饮食 (LPDs) 在延迟替代疗法 (KRT) 中的作用受到争议.
- 现实世界的数据对于了解LPD风险,实施和可行性至关重要.
研究的目的:
- 在晚期CKD患者中评估中度LPD (0.6-0.7g/kg/天) 的疗效.
- 为了比较采用LPD和不采用LPD的患者之间的存活率和透析启动.
- 评估在常规CKD护理中提供LPD的可行性和潜在益处.
主要方法:
- 对新转诊的晚期CKD患者的回顾性分析.
- 选择LPD的患者与不选择LPD的患者之间的结果比较.
- 对所有患者进行标准化的随访,不论饮食选择如何.
主要成果:
- 在182名患者中,有110名 (60.4%) 选择了LPD.
- 在LPD组中,估计的膜过率 (eGFR) 的下降速度较慢 (-0.89 vs -2.65 ml/min/1.73 m2/year).
- 对于LPD采用者来说,KRT需要 (84%),全因死亡率 (78%) 和死亡或透析复合结果 (81%) 显著减少.
结论:
- 超过60%的晚期CKD患者接受并遵循中度LPD,当提供.
- 坚持LPD与改善脏存活率和患者整体存活率有关.
- 虽然没有确定因果关系,但研究结果支持向慢性病患者提供LPD的可行性和潜在优势.
相关概念视频
01:25Chronic Kidney Disease I: Introduction
725
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
725
01:24Chronic Kidney Disease II: Clinical Manifestations
641
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
641
01:28Chronic Kidney Disease III: Interprofessional Care
466
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
466
01:18Chronic Kidney Disease IV: Nursing Management
388
Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
388
01:24Chronic Obstructive Pulmonary Disease
2.5K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
2.5K
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
3.7K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
3.7K