白血病性阴茎作为慢性淋巴性白血病的呈现症状
Harsahib Singh Sandhu1, Suresh Chandra2, Smiley Joshi3
1MBBS Intern, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Tiger Circle Road, Madhav Nagar, Manipal, Karnataka, 576104, India.
Journal of surgical case reports
|January 29, 2026
概括
慢性淋巴白血病 (CLL) 的罕见病例呈现为阴茎. 用acalabrutinib治疗实现了完全缓解,强调需要考虑阴茎病变中的白血病.
科学领域:
- 血液学 血液学 血液学
- 在瘤学瘤学.
- 皮肤病学 皮肤病学
背景情况:
- 慢性淋巴白血病 (CLL) 是西方国家最常见的白血病.
- 作为CLL的初始表现,阴茎前皮的参与是非常罕见的.
- 结核外和结核外的CLL表现不常见.
研究的目的:
- 报告一个非常罕见的CLL病例,呈现为阴茎损伤.
- 突出诊断的挑战和考虑白血病在阴茎的重要性.
- 为了证明acalabrutinib在治疗异常呈现的CLL中的有效性.
主要方法:
- 一名69岁的男性出现了不治愈的阴茎.
- 活检证实了小淋巴细胞淋巴瘤,导致进一步的血液学工作.
- 这名患者接受了阿卡拉布鲁丁尼布 (acalabrutinib) 的治疗,阿卡拉布鲁丁尼布 (acalabrutinib) 是一种布鲁顿氨酸激酶抑制剂.
主要成果:
- 血液学评估显示了CLL的潜在诊断.
- 患者在接受了7周的acalabrutinib治疗后实现了CLL的完全缓解.
- 阴茎在全身治疗CLL后消失.
结论:
- 阴茎病变可能是潜在的CLL的初始表现.
- 早期识别和诊断外骨髓性CLL至关重要.
- 使用acalabrutinib的向治疗对CLL是有效的,即使是在罕见的呈现.
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