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Updated: Jan 30, 2026

Deacetylation Assays to Unravel the Interplay between Sirtuins SIRT2 and Specific Protein-substrates
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通过CK2介导的HDAC5穿调节通过Ku70脱乙的DNA末端切除

Xueyi Liang1,2, Jingyuan Zhao1,2, Shoukang Li2,3

  • 1Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei, China.

Theranostics
|January 29, 2026
PubMed
概括

基因组脱乙酶5 (HDAC5) 通过脱乙Ku70来调节DNA修复途径的选择,影响胰腺癌治疗. 针对这种途径可以提高胰腺管道腺癌 (PDAC) 中的PARP抑制剂敏感性.

关键词:
在CK2中,CK2是CK2.在HDAC5中,HDAC5是指HDAC5.Ku70 Ku70 在线观看这是一种PARP抑制剂.胰腺管道腺癌瘤

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