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从神经发育的角度探索亨廷顿病

Chunhui Huang1, Xiao Zheng1, Wei Li1

  • 1The Sixth Affiliated Hospital of Jinan University, Dongguan, 523710, China; State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs, Guangdong Provincial Key Laboratory of Non-human Primate Research, Guangdong-Hong Kong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, 510632, China; Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, 510280, China.

International journal of biological sciences
|January 29, 2026
PubMed
概括

亨廷顿病 (HD) 可能源于发育问题,而不仅仅是神经元死亡. 在神经发育过程中准突变亨廷丁 (HTT) 为这种遗传性神经退行性疾病提供了新的治疗途径.

关键词:
HTT HTT 这样就好了.亨廷顿病就是亨廷顿病.动物模型动物模型大脑有机体 - - 大脑有机体早期干预是早期的干预.mHTT 的意思是神经发育的神经发育

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