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评估葡萄牙扩大HPV疫苗接种的公共经济收益:政府的视角分析
Nikolaos Kotsopoulos1,2, Mark P Connolly1,3, Andrew Pavelyev4
1Health Economics, Global Market Access Solutions Sàrl, Chardonne, Switzerland.
Journal of medical economics
|January 29, 2026
概括
在葡萄牙扩大人类乳头瘤病毒 (HPV) 疫苗接种提供了显著的经济效益. 目前的策略大大降低了疾病负担,通过将疫苗接种扩展到年轻成年人身上,可以获得进一步的收益.
科学领域:
- 公共卫生经济学 公共卫生经济学
- 流行病学 流行病学
- 卫生政策分析 卫生政策分析
背景情况:
- 人类乳头瘤病毒 (HPV) 感染是全球的主要公共卫生问题.
- 现有的HPV疫苗接种策略旨在减少与HPV相关的疾病发病率和死亡率.
- 了解疫苗接种计划的经济影响对于政策决策至关重要.
研究的目的:
- 评估葡萄牙扩大HPV疫苗接种范围对公共经济的影响.
- 为了比较当前的疫苗接种策略与没有疫苗接种和扩展的场景.
- 评估HPV疫苗接种的宏观经济 (社会) 和财政 (公共经济) 结果.
主要方法:
- 从社会和财政角度进行了成本效益分析.
- 一种动态传播模型 (DTM) 估计了100年的HPV相关疾病发病率和死亡率.
- 从降低发病率,死亡率,生产力损失和医疗保健成本获得的经济收益与疫苗接种费用进行了比较.
主要成果:
- 目前的国家免疫计划 (NIP) 预计将在100年内减少社会和财政疾病负担,分别为57.8%和59.9%.
- 将HPV疫苗接种范围扩大到26岁以下的男性和18-26岁未接种疫苗的女性,可以进一步减少1.24亿欧元和1.09亿欧元的社会和财政负担.
- 当前NIP的效益成本比率 (BCR) 为4.4 (社会) 和3.8 (财政);扩张收益率为1.9和1.7.
结论:
- 葡萄牙目前的HPV疫苗接种战略显示出了大量的公共卫生和经济效益.
- 将疫苗接种范围扩大到年轻的成年男性和未接种疫苗的女性提供额外的经济收益,超过了支出.
- 这些发现将公共卫生的好处转化为葡萄牙的积极宏观经济和财政结果.
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