在结膜黑色素瘤中降低环林激酶抑制剂p16INK4a和p27的下调

Emerentienne Sarrasin1, Elea Lalys1, Katya Nardou1

  • 1Department of Ophthalmology, Jules-Gonin Eye Hospital, FAA, University of Lausanne, Lausanne, Switzerland.

概括

在结膜黑色素瘤 (CJM) 中,p16INK4a和p27的损失与 nevi相比显著. 这些循环林依赖性激酶抑制剂可能有助于诊断,恢复p16INK4a功能可能会降低CJM的攻击性.

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