在老年膝关节骨关节炎患者中,中央敏感性是否会影响对生殖器射频和关节内注射的反应?
Ahmet Başarı1, Ayşe Seda Eren Zeydoğlu1
1Department of Algology, Kayseri City Hospital, Kayseri, Türkiye.
概括
中枢敏感性显著降低了老年人膝关节骨关节炎 (OA) 的治疗效果. 查中心敏感性可能会改善个性化治疗计划,以改善疼痛管理和功能.
科学领域:
- 老年医学 老年医学
- 疼痛管理 疼痛管理
- 再生医学是一种再生医学.
背景情况:
- 膝关节关节炎 (OA) 是老年人残疾的主要原因.
- 阴茎神经的射频剥离和关节内注射是常见的OA治疗方法.
- 中心敏感性可能会影响OA患者的治疗结果.
研究的目的:
- 评估中心敏感度水平对老年膝盖骨关节炎患者治疗反应的影响.
- 根据中央敏感化,评估生殖神经射频切除和关节内注射的疗效.
- 为了确定中央敏感化库存 (CSI) 评分是否能预测治疗结果.
主要方法:
- 对37名65岁以上膝关节OA患者进行了回顾性队列研究.
- 根据CSI得分 (<40和≥40) 患者被分为两组.
- 所有患者都接受了生殖神经射频切除和关节内注射,结果在基线和1,3个月评估.
主要成果:
- 所有患者在治疗后都显示出显著的临床改善 (p<0.001).
- 与较低得分 (p<0.001) 的患者相比,具有较高的CSI得分 (≥40) 的患者在疼痛,功能,睡眠和行走能力方面的改善明显较低.
- 回归分析证实,在所有测量参数上,较高的CSI得分预测治疗反应较差.
结论:
- 在老年人中,提高的中央敏感性显著损害了对生殖神经切除和注射膝关节OA的临床反应.
- 中央敏感化库存 (CSI) 可以识别可能具有低于最佳结果的患者.
- 将CSI查纳入治疗计划可能有助于个性化和更有效的OA管理策略.
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