在接受过导管 mitra 门治疗的患者中,左心室合规性和V 波反应的预测因素
Ziad Zalaquett1, Serge C Harb1, Maryam Majeed-Saidan1
1Department of Cardiovascular Medicine, Heart, Vascular, and Thoracic Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
JACC. Cardiovascular interventions
|January 29, 2026
概括
左下心房应变和先前心房动干预预测过导管 mitra 治疗 (TMVT) 的反应不佳. 这一发现有助于解释TMVT后的患者结果.
科学领域:
- 心脏病学 心脏病学
- 心血管外科心血管外科
- 医疗器械 医疗器械
背景情况:
- 肺毛细血管压力跟踪中升高的V波在严重的额头回 (MR) 中很常见.
- 这些波通常在过导管 mitra 治疗 (TMVT) 后减少.
- 尽管MR分辨率持久,但V波可能表明左心房 (LA) 符合性受损.
研究的目的:
- 为了确定侵入性LA合规性的非侵入性预测因素.
- 在接受TMVT的患者中确定V波反应的预测因子.
主要方法:
- 在2019-2023年期间对255名接受TMVT (边缘到边缘修复或门内) 的患者进行了回顾性分析.
- 根据基线LA平均压力和TMVT后的V波减压来分类为合规或不合规的患者.
- 多变量分析以确定低LA合规性的预测因素.
主要成果:
- 42%的患者有合规的LA,58%的患者有不合规的LA.
- 不合规的LA与心房动,先前的AF干预/LAA绑定,较低的LA储菌株和较差的LV纵向菌株有关.
- 低LA储菌株和之前的AF干预/LAA绑定预测了低侵入性LA合规性.
结论:
- 低LA菌株和先前的AF干预或LAA绑定可能预测TMVT后的低侵入性LA合规性和有限的V波减少.
- 符合LA似乎影响了对米特拉治疗的血液动力学和临床反应.
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