在墨西哥,谁可以使用PrEP? 分析用户的个人资料,并确定高风险的MSM中未能接触到的用户
Fernando Macías-González1, Heleen Vermandere2, Alicia Piñeirúa-Menendez2
1Center for Research on Population Health, National Institute of Public Health.
AIDS (London, England)
|January 29, 2026
概括
在墨西哥,公平地获得暴露前预防 (PrEP) 仍然是一个挑战. 该计划可能会错过高风险男性与男性发生性关系 (MSM) 的60%的人,特别是年轻和受教育程度较低的人.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 健康 公平 卫生 公平
背景情况:
- 暴露前预防 (PrEP) 是一种关键的艾滋病毒预防策略.
- 扩大墨西哥的PrEP计划面临着关于公平获取的挑战.
- 与男性发生性关系的高风险男性 (MSM) 是PrEP干预的优先人群.
研究的目的:
- 评估PrEP计划在墨西哥高风险MSM中的覆盖范围和公平性.
- 确定与PrEP获取相关的人口和地理因素.
- 量化高风险MSM在当前PrEP计划中可能无法达到的比例.
主要方法:
- 使用反事实预测和倾向得分匹配.
- 将PrEP使用者的非概率样本与高风险MSM的全国调查样本进行了比较.
- 分析了人口统计资料和地理位置,以评估计划的覆盖范围.
主要成果:
- 在高风险的MSM中,PrEP程序可能缺失高达60%.
- 年轻和受教育程度较低的MSM获得PrEP的可能性明显较低.
- 地理位置和个人资料是影响PrEP获取的关键因素.
结论:
- 在墨西哥,高风险的MSM在公平获得PrEP方面仍然存在重大差距.
- 需要有针对性的策略来改善服务不足的子组之间的PrEP吸收.
- 进一步的研究应侧重于了解易受伤害的MSM人群对PrEP获取障碍的障碍.
相关概念视频
Relative Risk
2.1K
Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
2.1K
Factors Affecting the Risk of Infection
13.5K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.5K
Ribosome Profiling
4.2K
Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
4.2K
Identifying Statistically Significant Differences: The F-Test
3.8K
The F-test is used to compare two sample variances to each other or compare the sample variance to the population variance. It is used to decide whether an indeterminate error can explain the difference in their values. The underlying assumptions that allow the use of the F-test include the data set or sets are normally distributed, and the data sets are independent of each other. The test statistic F is calculated by dividing one variance by another. In other words, the square of one standard...
3.8K
Taping Over Different Ground Profiles
375
Taping over varying ground profiles requires careful adaptation to achieve accurate measurements. On smooth, level ground with minimal vegetation, the tape can rest directly on the ground. Here, the taping team, typically consisting of a head and a rear tapeman, coordinates their positions with clear communication. The rear tapeman holds the tape at the starting point and guides the head tapeman toward a range pole placed beyond the endpoint, using hand or voice signals to ensure alignment.On...
375
Design Example: Analyzing Capacity Contours for Flood Risk Assessment
322
Flood risk assessment involves careful planning and analysis to ensure the safety of communities near water retention structures. Capacity contours are a vital tool in this process, as they illustrate the potential spread of water at specific levels in a given area. In the context of building a bund across a small valley, these contours play a critical role in evaluating the safety of nearby residential areas.In this example, the bund is intended to store stormwater in the valley. The engineers...
322


