血液学参数对地震相关创伤患者不良临床结果的预测值:一项回顾性研究
Ayşe Yılmaz1, Çağrı Safa Buyurgan2, Cüneyt Ayrık2
1Faculty of Medicine, Department of Emergency Medicine, Mersin University, Mersin, Turkey. ayra931117@gmail.com.
概括
中性粒细胞与淋巴细胞的比率 (NLR) 有效地预测地震创伤患者的不良结果. 这种随时可用的生物标志物有助于早期临床决策和灾难医学的资源配置.
科学领域:
- 紧急医疗 紧急医疗
- 创伤外科 手术 创伤外科
- 血液学 血液学 血液学
背景情况:
- 灾难环境,例如地震,会产生严重的创伤病例.
- 早期识别患有不良结果高风险的患者对于有效的资源分配和治疗至关重要.
研究的目的:
- 评估中性粒细胞与淋巴细胞比率 (NLR),血小板与淋巴细胞比率 (PLR) 和平均血小板体积 (MPV) 对地震相关创伤患者不良临床结果的预测值.
主要方法:
- 在地震后入院于默辛大学医院的成年创伤患者的回顾性分析.
- 收集的数据包括人口统计数据,实验室值 (NLR,PLR,MPV) 和不良结果 (拉布地质溶解,ACS,CS,AKI,透析,筋切割,截肢).
- 使用接收器操作特征 (ROC) 分析来评估NLR,PLR和MPV的预测性能.
主要成果:
- 中性粒细胞与淋巴细胞的比率 (NLR) 显示出对急性损伤 (AKI),透析,截肢和急性隔膜综合征 (ACS) 的强大预测能力.
- 血小板与淋巴细胞的比率 (PLR) 和平均血小板体积 (MPV) 对大多数不良结果显示中等到有限的预测值.
- 在此创伤队列中,NLR在预测重大不良临床事件方面始终优于PLR和MPV.
结论:
- 血液学生物标志物,特别是NLR,为识别灾后创伤的严重不良结果提供了重要的预后价值.
- 这些生物标志物的可访问性,低成本和易用性支持将它们纳入灾难应对期间的早期临床决策.
- 在大规模伤亡事件中,NLR可以帮助有效地分配资源和患者管理.
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