使用胸部X射线影像上部骨化估计年龄<3岁儿童骨成熟的一个实用提示:一个回顾性研究
Tomohiro Tsuru1, Shota Inoue1, Hiromi Edo2
1Department of Pediatrics, National Defense Medical College, Saitama, Japan.
European journal of pediatrics
|January 29, 2026
概括
评估幼儿的骨质年龄是一项挑战. 这项研究表明,胸部X射线上的部头部骨化提供了一种可靠的方法来估计三岁以下儿童的骨年龄.
科学领域:
- 儿科放射学 儿科放射学
- 骨的发育 骨的发育
- 医学成像分析 医学成像分析
背景情况:
- 在三岁以下的儿童中,骨龄的评估是很困难的,因为手骨化中心发达不足.
- 传统的基于手术的骨年龄评估方法往往不可靠,需要额外的成像.
研究的目的:
- 在3岁以下儿童的胸部X射线影像上使用部骨化来评估骨成熟模式与时间年龄的关系.
- 建立骨年龄评估的参考范围和估计公式.
主要方法:
- 从0至3岁的儿童对187张胸部X射线影像进行了回顾性审查.
- 通过三个读数器独立测量部头部骨骨化中心的纵向直径.
- 统计分析包括观察者间协议 (ICC),皮尔森相关性和线性回归.
主要成果:
- 在骨化中心直径和时间学年龄之间发现了强烈的正相关性 (r > 0.88).
- 获得了非常好的观察者间协议 (ICC = 0.96).
- 确定的参考范围 (±2 SD) 和具体的性别简化估计公式,用于实际临床使用.
结论:
- 常规的胸部X射线图提供了一个简单的,可复制的补充工具,用于评估三岁以下儿童的骨成熟.
- 这种方法可以在不需要额外的成像的情况下近似计算时间表年龄.
- 骨头骨化在这个年龄段提供了骨发育的强有力的指标.
更多相关视频
07:22Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
Published on: March 7, 2025
1.0K
10:57Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
Published on: August 22, 2012
24.4K
相关概念视频
Bone Formation by Intramembranous Ossification
10.7K
Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
10.7K
Flail Chest-I
708
Overview of Flail Chest
Flail chest is a severe and potentially life-threatening condition characterized by the fracture of three or more adjacent ribs in multiple places. It is most commonly caused by direct impacts and trauma, such as motor vehicle accidents or injuries from a steering wheel impact. It can also occur due to falls in elderly individuals with osteoporosis, or assaults involving sharp objects.
Pathophysiology
The pathophysiology of flail chest is complex, involving fractures of...
Flail chest is a severe and potentially life-threatening condition characterized by the fracture of three or more adjacent ribs in multiple places. It is most commonly caused by direct impacts and trauma, such as motor vehicle accidents or injuries from a steering wheel impact. It can also occur due to falls in elderly individuals with osteoporosis, or assaults involving sharp objects.
Pathophysiology
The pathophysiology of flail chest is complex, involving fractures of...
708
Flail Chest-II
616
Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:
Assessment:
1. Clinical Evaluation:
History:
616
Chest Physiotherapy
1.8K
Chest Physiotherapy (CPT) is a therapeutic technique used in respiratory care to improve ventilation, clear bronchial secretions, and enhance the efficiency of respiratory muscles. This therapy includes three primary procedures: postural drainage, percussion, and vibration. It can be performed on spontaneously breathing patients and those who are intubated and mechanically ventilated.
Purpose
CPT is primarily used for patients with excessive bronchial secretions who have difficulty clearing...
Purpose
CPT is primarily used for patients with excessive bronchial secretions who have difficulty clearing...
1.8K
Maturation of Endosomes
5.8K
The early endosome containing internalized molecules matures through transformations in its location, morphology, intraluminal pH, and membrane protein composition. Together, these changes result in a more acidic late endosome that contains multiple intraluminal vesicles; therefore, the late endosome is also called a multivesicular body (MVB).
Changes in location
The maturing endosome moves along microtubules from the periphery of the cell towards the perinuclear region. This movement of the...
Changes in location
The maturing endosome moves along microtubules from the periphery of the cell towards the perinuclear region. This movement of the...
5.8K
What are Estimates?
8.8K
It isn't easy to measure a parameter such as the mean height or the mean weight of a population. So, we draw samples from the population and calculate the mean height or mean weight of the individuals in the sample. This sample data acts as a representative measure of the population parameter. These sample statistics are known as estimates.
The estimate for the mean of a sample is denoted by ͞x, whereas the mean of the population is designated as μ. Further, parameters such...
The estimate for the mean of a sample is denoted by ͞x, whereas the mean of the population is designated as μ. Further, parameters such...
8.8K
