阻塞性睡眠呼吸暂停综合征对角膜敏感性和干眼参数的影响:全面分析
Ebubekir Durmuş1, Esma Ecem Ersoy2, Medine Çelebi Güneş1
1Department of Ophthalmology, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Turkey.
International ophthalmology
|January 29, 2026
概括
阻塞性睡眠呼吸暂停综合征 (OSAS) 并没有显著影响患者的干眼或角膜敏感性. 然而,眼产生与角膜神经之间的微妙联系表明,OSAS患者的潜在亚临床眼部变化.
科学领域:
- 眼科医生 眼科 眼科
- 睡眠医学 睡眠医学
- 眼睛表面疾病 眼睛表面疾病
背景情况:
- 阻塞性睡眠呼吸暂停综合征 (OSAS) 涉及呼吸道阻塞,导致间歇性缺氧,氧化应激和炎症.
- OSAS与各种眼部疾病有关,但其对干眼疾病 (DED) 和角膜敏感性的具体影响尚不清楚.
- 了解OSAS严重程度对眼表面健康的影响对于全面的患者管理至关重要.
研究的目的:
- 评估OSAS严重程度对干眼参数和角膜敏感性的影响.
- 探索OSAS,眼睛表面健康和系统/人口因素之间的关联.
主要方法:
- 一项涉及174名OSAS患者的横截面研究,这些患者的诊断是通过多睡眠学.
- 患者被分为正常-轻度和中度-重度OSAS组.
- 眼部评估包括撕裂时间 (NIBUT),希尔默II测试 (ST),眼部表面疾病指数 (OSDI) 和角膜敏感度测量.
主要成果:
- 中度至重度的OSAS患者年龄较大,BMI较高,氧和度较低.
- 在OSAS严重程度组之间没有发现NIBUT,ST或角膜敏感度的显著差异.
- 年龄和吸烟预测NIBUT;性别和氧和预测OSDI,表明微妙的系统影响.
结论:
- OSAS的严重程度并没有显著改变客观干眼测量或角膜敏感度.
- 眼产生和角膜神经功能之间的微妙关联表明潜在的亚临床眼部变化.
- 建议对OSAS患者进行例行眼科评估,特别是那些患有年龄,吸烟和低氧化等危险因素的患者.
更多相关视频
04:00Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings
Published on: August 2, 2024
3.2K
06:29Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19
Published on: May 25, 2022
2.8K
相关概念视频
Sleep Apnea
553
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
553
Noncompartmental Analysis: Miscellaneous Pharmacokinetic Parameters
451
The noncompartmental approach is a widely used method in pharmacokinetics to assess drugs' behaviors in the body. It considers several factors, including clearance, bioavailability, and total volume of distribution.
One key aspect of the noncompartmental approach is determining a drug's total clearance. This can be done by dividing the drug dose by the area under the concentration-time curve from zero to infinity. The area under the concentration-time curve represents the drug's...
One key aspect of the noncompartmental approach is determining a drug's total clearance. This can be done by dividing the drug dose by the area under the concentration-time curve from zero to infinity. The area under the concentration-time curve represents the drug's...
451
Insufficient Sleep and Sleep Deprivation
936
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
936
Stages of Sleep
1.4K
Sleep progresses through distinct stages, each characterized by specific brain wave patterns and physiological responses ranging from wakefulness to stages of non-rapid eye movement, known as non-REM, to rapid eye movement, referred to as REM. Understanding these stages helps in recognizing how sleep supports various bodily and cognitive functions.
Before sleep begins, in wakefulness, the brain exhibits primarily beta waves, which are high in frequency and low in amplitude, indicating alertness...
Before sleep begins, in wakefulness, the brain exhibits primarily beta waves, which are high in frequency and low in amplitude, indicating alertness...
1.4K
Impact of Groups on Groups
246
Social psychologists analyze how groups influence one another, shaping social structures and interactions through both cooperation and competition. These dynamics manifest in various ways, ranging from economic partnerships to intergroup conflicts that shape societal structures and perceptions.Cooperation and Competition in Intergroup RelationsIntergroup relationships vary across contexts, sometimes fostering cooperation and mutual benefit while at other times leading to conflict and...
246
Understanding Sleep
1.5K
Sleep, an essential biological state, involves significant reductions in physical activity, sensory awareness, and interaction with the environment. This complex physiological process is primarily regulated by specific brain regions, notably the hypothalamus and pons, which govern the sleep-wake cycle or circadian rhythm.
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
1.5K
