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一个系统的审查的种族多样性在临床试验参与在奥特罗亚的奥特罗亚
Selwyn Te Paa1, Tanira Kingi2, Joanna Nee Nee2
1Research Fellow, Medical Research Institute of New Zealand, Wellington, New Zealand; Health New Zealand - Te Whatu Ora Capital, Coast and Hutt Valley, Wellington, New Zealand.
The New Zealand medical journal
|January 29, 2026
概括
新西兰的临床试验缺乏足够的种族多样性,特别是毛利人和太平洋人民. 标准化的种族报告对健康公平和解决持续的不平等至关重要.
科学领域:
- 健康 公平 卫生 公平
- 临床试验研究 临床试验研究
- 公共卫生政策 公共卫生政策
背景情况:
- 临床试验中的多元种族代表性对于使研究与患者需求保持一致和促进健康公平至关重要.
- 澳大利亚新西兰毛利人面临的持续的健康不平等,需要在研究中改善种族代表性.
- 这项研究解决了在临床试验中公平参与的关键需求.
研究的目的:
- 从2010年至2020年在新西兰的随机对照试验 (RCT) 中,系统地审查民族代表性,重点关注毛利人和太平洋人民.
- 评估这些试验中种族报告的充分性和标准化.
- 为改善种族多样性和数据收集提供政策建议.
主要方法:
- 在新西兰进行的RCT (2010-2020) 的系统审查,在澳大利亚新西兰临床试验注册表 (ANZCTR) 登记并发表.
- 种族数据使用Stats NZ Tatauranga Aotearoa (Stats NZ) 一级或二级代码进行分类.
- 遵守系统审查和元分析 (PRISMA) 准则的首选报告项目.
主要成果:
- 在1040个确定的试验中,342个符合纳入标准;103个报告没有种族数据.
- 在239个包含的研究中,共有295,254名参与者:欧洲人 (6.1%),毛利人 (2.9%),太平洋人民 (1.4%),亚洲人 (7.5%),MELAA (2.5%),其他 (9.0%),残留 (70.6%).
- 观察到显著的代表性不足和高比例的未分类的种族数据.
结论:
- 新西兰临床试验中种族报告不足,缺乏标准化.
- 建议在新西兰的所有RCT中使用Stats NZ代码进行强制性种族报告.
- 这种标准化对于新西兰健康和残疾道德委员会,ANZCTR和期刊来说至关重要,以确保公平的研究实践.
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