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Updated: Jan 31, 2026

siRNA Screening to Identify Ubiquitin and Ubiquitin-like System Regulators of Biological Pathways in Cultured Mammalian Cells
10:43

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棕化介导的SRPK1的Ubiquitination调节高脂肪诱导的勃起功能障碍中的铁化

Xiao-Hui Tan1,2,3, Ke-Fan Li1,2,3, Yi-Ming Yuan1,2,3

  • 1Department of Urology, Peking University First Hospital, Beijing, P. R. China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|January 29, 2026
PubMed
概括

棕酸触发了血清氨基蛋白激酶1 (SRPK1) 的降解,促进了内皮细胞铁. 通过4'-O-Methylochnaflavone稳定SRPK1,可能为与脂质相关的疾病提供治疗效益.

关键词:
这就是SRPK1的原因.通过S-palmitoylation进行了S-palmitoylation的治疗.它们是内皮细胞的内皮细胞.这是勃起功能障碍.在 p53 里,p53 是一个 p53 的类型.

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