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Updated: Jan 31, 2026

Purification of Ubiquitinated p53 Proteins from Mammalian Cells
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Purification of Ubiquitinated p53 Proteins from Mammalian Cells

Published on: March 21, 2022

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针对p53-突变瘤的双通道向的Pro-ATO/Allicin脂质体

Xiaoling Xu1,2, WeiYi Cheng3, Menghang Yang1

  • 1Department of Radiation Oncology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|January 29, 2026
PubMed
概括

这项研究引入了一种结合三氧化和氨酸的新型纳米药物,以向p53-突变肺癌. 该配方重新激活突变的p53并抑制ATR,提高治疗效果并降低毒性.

关键词:
基因损伤反应 (DDR) 是一种对DNA损伤的反应.肺癌是一种肺癌.合成杀伤性 合成杀伤性艾利素是一种素.这就是p53突变.

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