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Updated: Jan 31, 2026

Pull-down of Calmodulin-binding Proteins
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生物催化四甲通过密码性青素结合蛋白类型thioesterases进行宏循环

Paisley L Jeannette1, Zachary L Budimir1, Lucas O Johnson1

  • 1James Tarpo Jr. and Margaret Tarpo Department of Chemistry, Purdue University, West Lafayette, Indiana 47906, United States.

Biochemistry
|January 29, 2026
PubMed
概括

研究人员使用生物信息学发现了WP516,一种新的硫酶酶. 这种酶有效地循环各种四甲,扩大产生循环四甲 (CTP) 的可能性.

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Factors Affecting Protein-Drug Binding: Protein-Related Factors

Drug binding to proteins is a key aspect of pharmacokinetics and can influence a drug's distribution, absorption, and elimination in the body. Several factors, including the drug's physiochemical properties, protein concentration, disease states, and the number of binding sites on the protein, influence this process.
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