固定与移动轴承膝关节整形:一个随机试验,至少10年后续
Konstantinos Tsikopoulos1, Konstantinos Kazamias2, Paul White3
12nd Orthopaedic Department, National and Kapodistrian University, Athens, Greece; Avon Orthopaedic Centre, Southmead Hospital, North Bristol NHS Trust, Bristol, United Kingdom.
The Journal of arthroplasty
|January 29, 2026
概括
这项研究发现,在固定轴承和移动轴承的膝关节全关节整形术 (TKA) 之间,在患者报告的结果或重新手术率中没有显著差异,长达19年. 这两种TKA类型都为骨关节炎患者提供了可比的长期结果.
科学领域:
- 整形外科手术 整形外科手术
- 生物医学工程 生物医学工程
- 临床试验 临床试验
背景情况:
- 移动轴承膝关节整形术使用移动阴茎轴承来增强旋转和转移.
- 固定与移动轴承平台在全膝关节整形术 (TKA) 中的临床优势尚不清楚.
- 这项研究旨在比较固定与移动轴承TKA在骨关节炎患者的结果.
研究的目的:
- 为了比较固定和移动轴承TKA之间的患者报告结果 (PROMs).
- 评估和比较两种TKA类型的并发症和修订率.
- 为了确定固定与移动轴承TKA的长期有效性和安全性.
主要方法:
- 一项随机试验涉及207名患者 (105名移动轴承TKA,102名固定轴承TKA) 从2001年至2006年.
- 主要结局:10年随访时的牛津膝盖得分 (OKS).
- 二次结局:WOMAC,布里斯托尔膝盖评分,术后并发症和植入物失败 (修复/移除) 长达19年.
主要成果:
- 在两年后的随访中,在OKS中观察到有利于固定轴承TKA的统计学上显著的差异 (平均差异3.6,P=0.0226).
- 经过19年的时间,各组的重新操作率没有显著差异 (风险比率1.51,P=0.2096).
- 在10年随访期间,PROM没有显著差异.
结论:
- 在两年随访后,固定和移动轴承TKA之间没有临床上有意义的差异.
- 在两种TKA类型之间在19年后的任何时间点内都没有观察到重新运行率的显著差异.
- 固定和移动轴承TKA都显示了可比的长期结果和骨关节炎的修订率.
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