在一般人群中,大动脉结石的患病率和风险因素的性别差异
Athena Adeli1, Eva Swahn2, Lars Lind3
1Cardiology Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Heart (British Cardiac Society)
|January 29, 2026
概括
与女性相比,男性患上大动脉结石 (AVC) 的患病率几乎是女性的两倍. 传统的心血管风险因素,如高脂蛋白,高血压和吸烟,在两性中都与AVC有关,BMI仅在男性中是因素.
科学领域:
- 心脏病学 心脏病学
- 流行病学 流行病学
- 图像成像是一种成像.
背景情况:
- 大动脉结石化 (AVC) 是大动脉狭窄之前的一种炎症过程.
- 男性的性别是已知的危险因素,但在AVC的性别特异性差异,特别是在年轻人群体中,需要进一步调查.
研究的目的:
- 在一般人群中研究大动脉结石化 (AVC) 发生率的性别特异性差异.
- 确定与AVC相关的传统心血管风险因素,并探索这些关联中潜在的基于性别的变化.
主要方法:
- 瑞典心肺生物影像研究队列的分析 (30,154名50-64岁的个人).
- 心脏CT成像用于确定AVC的存在.
- 逻辑回归用于评估心血管风险因素和AVC之间的关联,按性别分层.
主要成果:
- 风中风患病率在男性中为9%,在女性中为5%;男性性别是一个独立的预测因素 (OR 1.91).
- 脂质蛋白 (a),高脂血症,高血压和吸烟在两性中都与AVC有很强的关联.
- 身体质量指数 (BMI) 与男性的AVC有关,但与女性无关.
结论:
- 男性的性别独立地与近两倍高的AVC患病率有关.
- 传统的心血管风险因素在不同性别之间显示出与AVC的相似关联,BMI除外.
- 这些发现强调了在AVC风险评估和管理中考虑性别的重要性.
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