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Updated: Jan 31, 2026

Characterization of Neuronal Lysosome Interactome with Proximity Labeling Proteomics
11:40

Characterization of Neuronal Lysosome Interactome with Proximity Labeling Proteomics

Published on: June 23, 2022

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基于近距离的交互体 (Prob-PhI) 鉴定揭示了MEK1和MEK2的独特信号活动

Ying Wang1,2,3, Ping Xiao3,4, Ligang Fan5

  • 1Shaanxi Provincial Key Laboratory of Infection and Immune Diseases, Shaanxi Provincial People's Hospital, Xi'an 710068, China.

Analytical chemistry
|January 29, 2026
PubMed
概括

我们开发了一种新的方法,即基于近距离的相相互作用体 (Prob-PhI),用于识别酶基质. 试验结果显示MEK1和MEK2具有不同的作用,MEK2独特酸化LAMP3以调节 lysosomal 功能.

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Phospho Flow Cytometry with Fluorescent Cell Barcoding for Single Cell Signaling Analysis and Biomarker Discovery

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