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Updated: Jan 31, 2026

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需要ALKB-1-依赖的tRNA甲基化才能有效地消除父性线粒体

Zhenhuan Luo1,2,3, Yimin Li4,5, Chenyang He2,3,5

  • 1Department of Cardiology, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong, China.

Nature communications
|January 29, 2026
PubMed
概括

在C. elegans的繁殖过程中,DNA/RNA脱甲基酶ALKB-1对于去除父性线粒体至关重要. 它的缺失会破坏线粒体质量控制,影响生育能力和胚胎发育.

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