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Updated: Jan 31, 2026

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异常选择性的电压传感器捕获NaV1.5通道由Mg-protoporphyrin损害癌细胞迁移

Mahdi Jamili1, Marwa Ahmed1, Alisa Bernert1

  • 1Department of Biophysics, Center for Molecular Biomedicine, Friedrich Schiller University Jena and Jena University Hospital, Hans-Knöll-Straße 2, 07745, Jena, Germany.

Scientific reports
|January 29, 2026
PubMed
概括

2+-原PIX (MgPpIX) 强烈抑制了人类电压门的通道hNaV1.5,这是癌症的标. 这种特定的抑制剂显示出作为抗癌药物开发的化合物具有前途.

关键词:
这是SCN5A.癌症 癌症 癌症 癌症心脏的通道是心脏的通道静电面电位的电静电面电位.金属原氨酸是金属的原氨酸.分子动力学分子动力学电压传感器是一个电压传感器.

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