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Updated: Jan 31, 2026

Construction and Use of an Electrical Stimulation Chamber for Enhancing Osteogenic Differentiation in Mesenchymal Stem/Stromal Cells In Vitro
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Construction and Use of an Electrical Stimulation Chamber for Enhancing Osteogenic Differentiation in Mesenchymal Stem/Stromal Cells In Vitro

Published on: January 31, 2019

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PiR48444通过向METTL7A/eIF4E介导的BMP2 m6A甲基化来抑制MSC骨质分化和骨再生

Zhichao Zheng1,2, Xingyang Li1, Wenguang Qin1

  • 1School and Hospital of Stomatology, Guangdong Engineering Research Center of Oral Restoration and Reconstruction & Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou Medical University, Guangzhou, China.

Communications biology
|January 29, 2026
PubMed
概括

与Piwi相互作用的RNA 48444 (piR48444) 通过向METTL7A和BMP2mRNA甲基化来负面调节中酶干细胞 (MSC) 骨质生成. 它的抑制增强了骨再生,建议piR48444作为骨修复的治疗点.

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