严重甲状腺功能低下和神经昏迷的住院患者的心室功能
Joaquin Lado-Abeal1, Irsa Munir2, Khalid Al-Zubaidi1
1Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, University of California Davis Medical Center and School of Medicine, California, USA.
The Journal of clinical endocrinology and metabolism
|January 30, 2026
概括
严重的甲状腺功能低下症经常导致心脏功能障碍,影响心缩和心缩功能以及心肌变形. 尽管存在这些异常,但严重甲状腺功能低下症患者的短期死亡率仍然很低.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 医疗成像医学成像
背景情况:
- 甲状腺激素对人类心脏功能的内效应的临床意义尚未完全理解.
- 严重的甲状腺功能低下和神经昏迷会显著影响心脏表现.
研究的目的:
- 为了评估患有严重甲状腺功能低下和神经昏迷的患者的腹腔功能.
- 通过心声学来评估心缩和心缩功能和心肌变形.
主要方法:
- 一个多中心的,回顾性横截面研究,涉及112名入住ICU的严重甲状腺功能低下的成年患者.
- 胸外心声学 (TTE) 和斑点跟踪心声学 (STE) 用于分析左心室 (LV) 和右心室 (RV) 功能和全球纵向应变 (GLS).
主要成果:
- 68.2%的患者显示LV GLS受损,34.0%的患者显示VR GLS受损.
- 在37.5%的患者中观察到LV射出分数 (LVEF) 降低,在66.7%的患者中观察到LV透析功能异常.
- 心血管药物与心声回声学发现有关,可能是由于混因素.
结论:
- 严重的甲状腺功能低下与广泛的静脉缩和静脉缩腹腔功能障碍以及心肌变形受损有关.
- 药物和心脏异常之间观察到的关联可能是由于潜在的患者疾病而不是直接的药物效应.
- 短期死亡率很低,尽管在这个患者队列中存在显著的心脏异常.
相关概念视频
Hospitals-II
1.2K
Hospitals provide inpatient and outpatient services. Inpatient services provide care to patients that stay in the hospital for an extended period, ranging from days to months. Examples of inpatient services include intensive care units, hospital wards, or surgeries. Outpatient services provide care to patients who come to a hospital for a diagnostic or treatment but do not stay overnight —for example, diagnostic tests, surgical procedures, or health education.
Nurses that work in...
Nurses that work in...
1.2K
Hospitals-I
1.6K
Hospitals offer medical and surgical care to the sick and injured, along with accommodation while they recover. At the same time, they also provide outpatient, emergency, psychiatric, and rehabilitation services to meet various community needs. In addition to providing medical care, hospitals also act as hubs for medical research and training. Hospitals use clinical procedures and evidence-based practice standards to deliver patient care. To deliver safe and efficient care, a nurse must stay up...
1.6K
Anatomy of the Heart
119.7K
The human heart is made up of three layers of tissue that are surrounded by the pericardium, a membrane that protects and confines the heart. The outermost layer, closest to the pericardium, is the epicardium. The pericardial cavity separates the pericardium from the epicardium. Beneath the epicardium is the myocardium, the middle layer, and the endocardium, the innermost layer. There are four chambers of the heart: the right atrium, the right ventricle, the left atrium, and the left ventricle.
119.7K
Anatomy of the Heart
3.1K
The heart is a hollow, muscular organ approximately the size of a fist, consisting of four chambers. It is enclosed in the pericardium, a fibrous sac with two layers: the visceral and parietal pericardium, separated by a fluid-filled space containing serous fluid to reduce friction.
The heart has three layers: the innermost endocardium, the muscular myocardium, and the outer epicardium, all working together for optimal cardiac function.
Chambers of the Heart
The heart is made up of four...
The heart has three layers: the innermost endocardium, the muscular myocardium, and the outer epicardium, all working together for optimal cardiac function.
Chambers of the Heart
The heart is made up of four...
3.1K
Overview of the Heart
13.8K
The heart, a muscular organ located in the chest, functions as the body's pump, circulating blood through the vascular system. It has four chambers: two atria on top and two ventricles below. The right atrium receives deoxygenated blood from the body and passes it to the right ventricle, which pumps it to the lungs for oxygenation. The left atrium receives oxygenated blood from the lungs and transfers it to the left ventricle, which pumps it to the rest of the body.
The heart's structure...
The heart's structure...
13.8K
Conduction System of the Heart
13.3K
Autorhythmicity is a term that refers to the heart's inherent ability to generate electrical signals and instigate muscle contractions. This self-regulating conduction system within the heart consists of two key components: the pacemaker cells and specialized conducting cells.
The pacemaker cells are located in two primary nodes: the sinoatrial (SA) node and the atrioventricular (AV) node. The SA node pacemaker cells can autonomously depolarize, triggering an action potential that leads to the...
The pacemaker cells are located in two primary nodes: the sinoatrial (SA) node and the atrioventricular (AV) node. The SA node pacemaker cells can autonomously depolarize, triggering an action potential that leads to the...
13.3K


