维生素D缺乏对老年患者认知和神经肌肉功能的影响
Mohamed Ghalib Zakaria1, Bassam Taha Saleh1, Abdulsattar Hussein Abdullah1
1Department of Medicine, College of Medicine, University of Tikrit, Iraq.
Neuro-Signals
|January 30, 2026
概括
维生素D缺乏症在老年人中很常见,并且与较差的认知和神经肌肉功能有关. 解决维生素D水平可能会支持老年人群中的大脑和肌肉健康.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 内分泌学 在内分泌学.
背景情况:
- 维生素D对于神经元和神经肌肉信号传递至关重要,影响平衡和神经炎症.
- 维生素D缺乏在老年人中很普遍,与认知能力下降,神经肌肉功能下降和炎症增加有关.
研究的目的:
- 研究血清25-基维生素D水平与老年人认知表现,神经肌肉功能和炎症标志物之间的关联.
主要方法:
- 一项对250名65-85岁成年人进行的横截面研究评估了认知功能 (MMSE,MoCA),神经肌肉性能 (握手,步行速度,TUG,BIA,EMG) 和血清生物标志物 (25(OH) D,,PTH,CRP,IL-6).
主要成果:
- 维生素D缺乏 (62.0%) 与较低的认知评分,较弱的神经肌肉性能,改变的代谢和升高的炎症标志物有关.
- 在维生素D水平和认知/神经肌肉结果之间发现了积极的相关性.
- 在维生素D水平和炎症标志物之间观察到负相关性.
结论:
- 老年人维生素D缺乏与认知和神经肌肉功能受损有关.
- 失调的信号传递和增加的神经炎症可能会调解这些效应.
- 维生素D的状态与神经元和神经肌肉通信通路有机械联系.
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