一个前性的国际多站点随机控制试验,在腺瘤检测中,与和没有远端盖的交换水
Felix W Leung1,2,3, Sergio Cadoni4, Long Chen5
1Gastroenterology, Medicine, Sepulveda Ambulatory Care Center, Veterans Affairs Greater Los Angeles Healthcare System, North Hills, CA, USA (Felix W. Leung, Vivek Dixit, Nora Jamgotchian, Hui Jia).
Annals of gastroenterology
|January 30, 2026
概括
在结肠镜检查期间添加特殊的盖子,如DaisycuffTM和CAP,显著增加了腺瘤检测率 (ADR),特别是在右结肠. 这些发现可能有助于通过改善腺瘤检测来减少间隔癌症.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 预防癌症 预防癌症
背景情况:
- 间隔癌症是一种与低腺瘤检测率 (ADR) 相关的担忧.
- 水交换和直帽 (CAP) 可能会改善ADR,但DaisycuffTM和Endocuff Vision®的影响是未知的.
- 这项研究调查了特定的上限是否可以增强ADR和水交换结果.
研究的目的:
- 评估不同封顶在改善结肠镜检查期间腺瘤检测率 (ADR) 的有效性.
- 为了比较使用No cap与CAP,DaisycuffTM和Endocuff Vision®实现的ADR.
- 评估盖子对不同结肠部分腺瘤检测的影响.
主要方法:
- 结肠镜检查程序被随机分配到多个地点的No cap,CAP,DaisycuffTM或Endocuff Vision®组.
- 测量的主要结果是腺瘤检测率 (ADR).
- 每次结肠镜检查的腺瘤和检测率在没有帽子组和增加帽子组之间进行了比较.
主要成果:
- 没有上限组的ADR总体 (45.6%) 超过了基准 (35%).
- 戴西手套TM (52.8%) 和CAP显著增加了右结肠的不良反应.
- 戴西手套TM还显著增加了左结肠在结肠镜检查中的腺瘤.
结论:
- 由于较高的右结肠ADR,CAP和DaisycuffTM对减少间隔癌症具有潜在的临床相关性.
- 虽然有或没有盖的水交换超过了基准,但需要进一步确认盖的有效性.
- 选择的盖子可以提供额外的选择,以改善结肠镜检查结果和水交换效率.
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