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在结肠直肠癌中,关于腹转移有什么值得知道的?

Michał Stańczak^1,2, Wiesław Kruszewski^1,2, Maciej Ciesielski^1,2

¹Oncological Surgery Department, Medical University of Gdansk, Gdańsk, Poland.

Frontiers in surgery

|January 30, 2026

概括

结肠直肠癌 (CRC) 产生的腹膜转移 (PM) 存在挑战,但诊断和腹膜内疗法的进步为选定的患者提供了更好的生存率. 多学科的护理和持续的研究是改善PM的CRC治疗结果的关键.

科学领域:

在瘤学瘤学.
手术瘤学手术瘤学
胃肠病学胃肠病学

背景情况:

由结直肠癌 (CRC) 引起的腹转移 (PM) 是一个严重的临床挑战,预后不佳.
甲状腺细菌以同步和超时的速度发生,腹膜是肝脏之后的第二个最常见的转移部位.
患PM的危险因素包括右侧结肠瘤,BRAF突变和粘膜组织学.

研究的目的:

审查PM的CRC患者的病理生理学,危险因素,诊断策略和治疗选择.
突出了PM的诊断,手术技术和腹腔内治疗的最新进展.
讨论腹癌指数 (PCI) 和新兴治疗方法的预后意义.

主要方法:

关于结肠直肠癌腹转移的当前文献的综述.
分析包括CT,MRI,PET/CT和腹腔镜在内的诊断方式.
评估治疗策略,如细胞还原性手术 (CRS),高热性腹腔内化疗 (HIPEC) 和加压腹腔内气溶化疗 (PIPAC).

主要成果:

带有或没有高热性腹腔内化学疗法 (HIPEC) 的细胞还原性手术 (CRS) 改善了受限PCI的选定患者的生存率.
腹癌指数 (PCI) 对于预后和治疗决策至关重要.
像PIPAC这样的新兴疗法显示出希望,而HIPEC的作用仍在争论中.

结论:

优化CRC与PM的结果需要由多学科团队在专业中心进行管理.
以生物标志物为基础的个性化治疗策略对于改善患者预后至关重要.
对分子预测因子和新型药物输送的持续研究对于推进医疗保健至关重要.

关键词:

头 - 头 - 头 - 头皮帕克 (PIPAC) 是一个国际组织.结肠直肠癌是什么意思细胞减小手术细胞减小手术腹内转移的发生.

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