便携式动态激光光斑成像仪用于快速抗菌感应性测试
Jinkai Yang1,2, Keren Zhou1,2, Landon Hernandez1,2
1School of Electrical Engineering and Computer Science, The Pennsylvania State University, University Park, Pennsylvania 16802, United States of America.
本研究介绍了一种便携式动态激光光斑成像设备,用于快速抗菌素敏感性测试 (AST). 3D打印系统在2-3小时内提供准确的结果,有助于点的护理诊断.
科学领域:
- 生物医学工程 生物医学工程
- 微生物学 微生物学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 抗菌素耐药性 (AMR) 是一个关键的全球卫生问题.
- 目前的抗微生物敏感性测试 (AST) 方法缓慢,需要实验室设施,限制在资源有限的地区使用.
研究的目的:
- 开发一种快速,便携且具有成本效益的用于抗微生物敏感性测试 (AST) 的设备.
- 为了在护理点能够及时做出诊断决策.
主要方法:
- 一个3D打印的便携式动态激光光斑成像 (pDLSI) 设备被设计和制造.
- 细菌活动诱导的斑点波动是通过手机摄像头捕获的.
- 机器学习分析了时空折叠关系图,以确定最小抑制度 (MIC).
主要成果:
- 该pDLSI装置在2-3小时内确定了格拉姆阳性和格拉姆阴性细菌的MIC.
- 使用 *Enterococcus faecalis *, *Escherichia coli *,安培和 gentamicin 验证了性能.
- 该设备显示了快速AST的潜力.
结论:
- 便携式动态激光光斑成像 (pDLSI) 系统提供了一种快速且易于使用的抗菌感应性测试 (AST) 方法.
- 它的简单设计和便携性促进了临床诊断,解决了传统方法的局限性.
更多相关视频
11:25Preparation of a Blood Culture Pellet for Rapid Bacterial Identification and Antibiotic Susceptibility Testing
Published on: October 15, 2014
12:39Antimicrobial Susceptibility Testing of Mycobacterium Tuberculosis Complex for First and Second Line Drugs by Broth Dilution in a Microtiter Plate Format
Published on: June 24, 2011
相关概念视频
Antimicrobial Effectiveness
Magnetic Susceptibility and Permeability
When diamagnetic materials are placed under an external magnetic field, the moments opposite to the field are induced. Hence, the susceptibility for diamagnets has a minimal negative value of 10-5–10-6. Since...
Antimicrobial Proteins
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Susceptibility, Permittivity and Dielectric Constant
Dynamic Equilibrium
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents
