相关实验视频
Updated: Jun 9, 2026

09:41
Reconstitution Of β-catenin Degradation In Xenopus Egg Extract
Published on: June 17, 2014
概括
这项研究纠正了先前发表的一篇文章DOI. 校正确保了科学研究的准确引用和引用. 通过更正的DOI提供更多细节.
科学领域:
- 科学出版业的科学出版.
- 学术传播学术交流
- 图书统计学 图书统计学
背景情况:
- 准确的引用对于科学完整性至关重要.
- 数字物体识别器 (DOI) 确保对研究文章的持续和可靠访问.
- 在DOI中的错误可能会阻碍引用跟踪和影响评估.
研究的目的:
- 为现有文章的DOI提供纠正.
- 确保研究的适当归因和可发现性.
- 为了保持科学文献记录的准确性.
主要方法:
- 发出了一份正式的纠正通知.
- 错误的DOI被确定并用正确的DOI取代.
- 纠正通过适当的道公布.
主要成果:
- 文章DOI已经正式纠正.
- 修正后的DOI现在可供准确引用.
- 这确保了科学记录的完整性.
结论:
- 准确的DOI对于科学发现的可复制性和可追溯性至关重要.
- 这次校正符合学术出版的标准.
- 研究人员应该始终验证DOI以确保准确的引用.
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Mismatch Repair
Overview
Proofreading
Synthesis of new DNA molecules starts when DNA polymerase links nucleotides together in a sequence that is complementary to the template DNA strand. DNA polymerase has a higher affinity for the correct base to ensure fidelity in DNA replication. The DNA polymerase furthermore proofreads during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.Errors during Replication Are Corrected by the DNA Polymerase EnzymeGenomic DNA is synthesized in...
Proofreading
Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore, it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
Errors During Replication are Corrected by the DNA Polymerase Enzyme
Errors During Replication are Corrected by the DNA Polymerase Enzyme
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The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
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