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Updated: Jan 31, 2026

Macrophage Differentiation and Polarization into an M2-Like Phenotype using a Human Monocyte-Like THP-1 Leukemia Cell Line
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Macrophage Differentiation and Polarization into an M2-Like Phenotype using a Human Monocyte-Like THP-1 Leukemia Cell Line

Published on: August 2, 2021

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肝细胞癌中的SDHA缺乏促进瘤通过酸盐诱导的M2巨细胞极化进展

Xinyang Li1,2,3, Luyuan Ma1,2,3, Chuan Shen1,2,3

  • 1Department of Infectious Diseases, Hebei Medical University Third Hospital, Shijiazhuang, 050000, China.

Oncology research
|January 30, 2026
PubMed
概括

肝细胞癌 (HCC) 的进展是由代谢变化驱动的. 苏酸脱酶A (SDHA) 缺乏通过GPR91/STAT3通路促进M2巨的两极分化,增加HCC风险. 血清酸盐可以作为诊断标记物.

关键词:
G蛋白结合受体91 (GPR91) 是一种G蛋白结合受体.肝细胞癌是肝细胞癌.在M2巨细胞中.代谢重编程是指代谢重编程.顺酸是什么意思 顺酸苏酸脱酶复合体亚单元A (SDHA) 的作用.瘤微环境是一个微环境.

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