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Updated: Jan 31, 2026

Author Spotlight: Unveiling the Structural and Dynamic Aspects of Glycan Molecular Recognition
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Author Spotlight: Unveiling the Structural and Dynamic Aspects of Glycan Molecular Recognition

Published on: May 17, 2024

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介绍:在分子和细胞层面上识别甘氨酸-乳氨酸是必不可少的:与瘤相关的O-甘氨酸与巨细胞糖类乳氨酸的相互作用

Ana Sofia Grosso1,2, Ana Diniz1,2, Cátia O Soares1,2

  • 1UCIBIO - Applied Molecular Biosciences Unit, Department of Chemistry, NOVA School of Science and Technology, NOVA University Lisbon, 2829-516 Caparica, Portugal.

JACS Au
|January 30, 2026
PubMed
概括

人类巨细胞的银糖类型的莱克 (MGL) 与瘤相关的森新 (Tn) O-甘氨酸比化变体 (STn) 或森-弗里登里希 (TF) O-甘氨酸更强烈地结合. MGL作为截断癌症相关的O-甘氨酸的通用受体.

关键词:
糖甘和受体呈现方式巨细胞的银河糖类型的莱克.分子识别分子识别与瘤相关的O-甘氨酸.

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