相关实验视频

Updated: Jan 31, 2026

Generation of Alpha-Synuclein Preformed Fibrils from Monomers and Use In Vivo
09:44

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Published on: June 2, 2019

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在S129的α-Synuclein纤维的酸化改变了通过固态NMR探测的DNAJB1结合

Sayuri Pacheco1, Dhanya S Reselammal1, Shanlong Li2

  • 1Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States.

JACS Au
|January 30, 2026
PubMed
概括

在S129的α-synuclein纤维的酸化降低了C端动力学,并增强了cochaperone DNAJB1的结合,有助于用于神经退行性疾病研究的伴侣识别.

关键词:
DNAJB1 DNAJB1 的意思它们是J蛋白质.粉样蛋白纤维的纤维.陪伴者是一个陪伴者.酸化的方法是:光化.翻译后的修改 翻译后的修改固态NMR是一种固态NMR.α-synuclein 是一种同核蛋白.

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