年轻人内化症状的等级维度的神经结构基质
E Leighton Durham1, Tyler M Moore2, Kaitlynn E Ellis1
1Department of Psychology, Vanderbilt University, Nashville, Tennessee, USA.
Human brain mapping
|January 30, 2026
概括
儿童内化症状,如痛苦和恐惧,与大脑结构的差异有关. 这项研究揭示了这些症状如何与青少年的灰质体积和表面积有关.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 儿童精神病学 儿童精神病学
背景情况:
- 内化症状在儿童时期普遍存在,并与大脑结构变异有关.
- 这些年轻人症状的组织和神经生物学基础需要进一步调查.
- 维度,跨诊断和层次模型越来越多地用于内化精神病理学.
研究的目的:
- 检查9至10岁儿童内化症状的因子结构.
- 为了确定内化症状因素的神经结构相关性.
- 为了研究层次层次的维度方法在中年儿童的实用性.
主要方法:
- 使用了来自青少年大脑认知发展 (ABCD) 研究的大量样本 (N=11,868).
- 采用高阶建模来分析痛苦,认知,恐惧和体质症状因素.
- 评估区域灰质体积,皮质厚度和皮质表面积,控制共变量.
主要成果:
- 一般的内化,痛苦和认知症状与减少的灰质体积和皮质表面积相关.
- 恐惧症状与,和岛屿区域的表面积较小有关.
- 皮层厚度和体质症状显示神经结构关联不那么一致.
结论:
- 层次层次的维度模型有效地捕捉了青年人内化症状的组织.
- 特定的内化症状因素与神经结构变异的不同模式有关.
- 研究结果支持分层方法的实用性,以了解中儿童时期内化症状的神经基质.
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