用自扩展导航器门植入节拍器的植入率
Michael Paukovitsch1, Moritz Konjack1, Dominik Felbel1
1Department of Cardiology Ulm University Heart Center Albert-Einstein-Allee 23 89081 Ulm Germany.
Journal of the American Heart Association
|January 30, 2026
概括
与Evolut系统相比,用Navitor自扩展替换过导管大动脉的永久起器植入 (PPI) 率更高. 高植入深度可能会降低Navitor的PPI率,使得结果与其他自扩展相提并论.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 生物医学工程 生物医学工程
背景情况:
- 跨导管大动脉置换 (TAVR) 中的自扩展与比气球扩展系统更高的永久起器植入 (PPI) 率有关.
- 纳维托假肢是一种新的,管状的自扩展门,在临床上越来越多地使用.
研究的目的:
- 为了比较Navitor和Evolut自扩展TAVR系统之间的30天PPI率.
- 为了调查影响PPI率的因素,使用Navitor假肢.
主要方法:
- 一项对148名接受Navitor系统和165名接受Evolut系统的患者进行的比较研究.
- 排除具有先前存在的PPI,高风险心电图或特定假肢尺寸的患者.
- 多变量后勤回归分析以调整基线差异.
主要成果:
- 纳维特组年龄较大,预测死亡风险较高.
- 总体PPI比率在Navitor (17.6%) 与Evolut (6.7%) 之间显着更高,在调整后仍然存在.
- 在小环形患者中,PPI率在两种系统之间相似.
- 在使用较大的Navitor假肢 (27/29mm) 时观察到更高的PPI率.
- 更深的植入深度与Navitor队列中较低的PPI率有关.
结论:
- 导航器TAVR可能具有与其他自扩展相比较的PPI率,具体取决于假肢尺寸.
- 优化Navitor假肢的植入深度可能会降低PPI率.
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